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Request permissions. Synthesis, properties, and optical applications of low-dimensional perovskites Y. Zhang, J. Liu, Z. Wang, Y. Xue, Q. Ou, L. Polavarapu, J. Zheng, X. Qi and Q. Bao, Chem. Search articles by author Yupeng Zhang. Jingying Liu. Ziyu Wang. Yunzhou Xue. Qingdong Ou. Lakshminarayana Polavarapu. Jialu Zheng. Xiang Qi. Qiaoliang Bao. Back to tab navigation Fetching data from CrossRef.

Back to tab navigation. He can decide to choose the right type one for wound treatment by assessing the wound situation of each patient.


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In the process of wound treatment, there are many different types of dressings such as foams [ 15 ], gauze [ 8 , 14 ], transparent films [ 9 , 17 ], alginates [ 17 ], composites, hydrocolloids [ 27 ] and hydrogel Table 1 [ 7 , 16 ]. Whether to use a particular dressing is the most difficult in wound management.

Thus, it is important and necessary to understand the types and characteristics of dressings and their indications, and the advantages and disadvantages of each wound dressing. Here, we will introduce various wound dressings commonly used in our case treatments. Foam dressings are made of polymer material and are usually multi-layer structures, which are consisting of anti-adhesion wound contact layer, infiltration layer and waterproof and germresistant layer Table 1 [ 6 , 15 , 24 ]. The surface is often covered with one layer polymeric semi-permeable membrane.

Some of them are self-adhesive, with the main ingredients being silica gel and so on. Its action mechanism is that the absorptive foam absorbs a large amount of exudate, reduces infiltration, and provides a moist, warm and closed wound healing environment. Foam dressing is suitable for wounds with medium to large amount of exudates. The dressings can be used for the treatment and prevention of pressure ulcer, diabetic foot ulcer, skin donor area, mild burn, skin transplant, venous ulcer etc.

The advantages of foam dressing are able to provide a moist and closed healing environment and support autolysis debridement. And also with its high absorptivity, it can absorb medium to large amount of exudates and reduce the influence of exudates and impregnation on wounds. A low frequency of dressing replacement is required. It is convenient for treatment of different wound sites, with different shapes and sizes. They are not easy to be adhered to the wound bed.

Form dressing is also easy to use with good compliance, and easy to tear off without hurting the skin. The disadvantages are that the external dressing is needed for the non-adhesive edge or to use two layers of dressing or adhesive tape. And it is opaque and the wound cannot be observed directly. Once large leakage happens or dressing replacement is delayed, it may cause skin around the wound impregnated. This dressing is not suitable for eschar or dry wounds.

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Gauze dressings are made of braided or non-braided materials, mostly cotton, with multiple shapes and sizes Table 1. Gauze is suitable for one-time use in cleaning, hemostasis bandaging or hygienic care of surgical or local wounds Figure 2 [ 8 , 14 ]. It is helpful for wound infection, wound protection, wound exudate management. Gauze is actually useful for many kinds of wounds. They are easily available with low price. Gauze dressing can protect wounds and reduce bacterial invasion.

It is cheap and suitable for various consumption levels. The disadvantages are that this type of dressing is required for frequent replacement that increases the total cost. And it may adhere to the wound bed. Gauze dressing often needs to be combined with other types of dressings; it cannot be used for wet wound healing.

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Their barrier functions are poor with high possibility of germ invasion. The granulation tissue of wound is easy to grow into the mesh eye of gauze. It will damage the newborn tissue and cause pain during dressing replacement. The sticky wound may cause not only pain but also secondary trauma during dressing replacement. Composite dressings are made of any kind of dressing materials, such as a combination of foam and gauze, alginate and silver ion dressing, alginate and carboxymethyl cellulose sodium CMC.

Composite dressings can be used as one-layer or two-layer dressing and for a variety of wound types [ 11 , 17 ].

This dressing is a new type of interactive wound-cleaning dressing. With its outer layer being a hydrophobic synthetic fiber material, the core part of which is polypropylene acid ester SAP. SAP has a high affinity for proteins and can actively absorb wound exudates and necrotic tissues. Its indications are grade II burn wounds, small area grade III burn wounds, surgical wounds such as skin necrosis after operation, treatment of infectious wounds , refractory chronic wounds such as diabetic gangrene, deep pressure ulcer, refractory ulcer [ 25 ].

Particularly, this dressing is good for debridement of rotten granulation wounds and old granulation wounds.


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  6. Its advantages are easy to use with continuous debridement, accelerating necrotic tissue exfoliation, controlling germ infection and promoting wound healing [ 25 ]. There is effective protection of skin grafts in recipient areas to prevent infection and necrosis.

    The Wound Dressings and Their Applications in Wound Healing and Management

    Also, this dressing does not stick to the wound bed. Its disadvantages are higher price, lower cost performance and lower flexibility of indications. The dressings need daily replacement and are not suitable for wounds with vascular exposure on the wound surface, especially those with partial vascular embolism and necrosis. The alginate dressings are composed of the extracts of natural brown algaemainly polysaccharide Figure 2.

    They are braided or non-braided. These dressings have strong infiltration capacity and may become gelatinous after contacted with exudate fluid [ 17 ,18].

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    They can be used for the treatment of venous ulcer, sinus wound and severe exudate wound [ 10 ]. Their action mechanism is mainly through the exchange of sodium ions and water in wound exudates with calcium ions in alginate dressings, to make calcium alginate become gel, provide moist healing environment, promote cell proliferation at wound area, reduce pain, protect new tissue from injury and accelerate wound healing. Plus, macrophages are activated by fibrous stimulation of gel and calcium alginate, and further remove infectious tissue and scab crust, promote the release of growth factors, and promote the proliferation of fibroblasts and keratinocytes and accelerate healing.

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    Alginate dressings are applied to treat superficial wounds, wounds with skin removal, the wounds with medium to large amount of exudates, the wounds with holes and sinuses, the infectious wounds with necrotic tissue or cancerous wounds. Alginate dressings have strong absorptive capacity to absorb a large amount of infiltration.

    The ion exchange between sodium and calcium occurs after dressings contacting with exudate, which releases calcium ion and plays the role of hemostasis and stabilization of biomembrane. Dressings can form gel on wound bed and provide a wet healing environment to keep nerve endings moist, relieve pain, avoid dehydration and promote epithelial regeneration. These dressings can form hydrates with necrotic tissues to promote wound autolysis and debridement [ 18 ]. These dressings are also convenient to use and easy to remove, with no toxicity and no allergy.

    They can be used for infective wounds and non-adherent wounds, and they also promote autolysis debridement. However, these dressings need a second layer of dressing. They cannot be used for wounds with small amount of exudate and dry eschar wounds. Gel may not be distinguished from germ infection. It may cause dehydration and dry wound beds. These dressings misused to exposed tendons, key capsules or bones, may cause necrosis of these tissues. Figure 2: Various wound dressings. The ingredient of the hydrocolloid dressings Figure 2 is mainly carboxymethyl cellulose sodium CMC [ 28 ].

    Flake hydrocolloid is composed of CMC, hypoallergenic medical adhesive gel, elastomer and plasticizer. Its surface is a layer of semi-permeable poly membrane structure. The hydrocolloid dressings contain colloidal particles, such as gelatin or pectin, which can be transformed into gel-like substance when contacted with exudate.

    Thus, hydrocolloid dressings display certain exudate absorptive capacity, as well as having strong stickiness [ 6 , 13 ].